ABSTRACT
Abstract In this paper I propose a reflection on instruments and political power. The objective is to analyze how the knowledge, experiences, and practices that circulated and traveled via radioactivity counters between Italy and Spain constructed and influenced both nuclear energy and political power during the Franco regime. I show people, materials, instruments, and knowledge that traveled, which permits us to think about the Spanish scientists and their role in the circulation of scientific materials and knowledge and as vectors of diplomatic and political relations.
Resumo Este artigo propõe uma reflexão sobre os instrumentos e o poder político. O objetivo é analisar como o conhecimento, as experiências, e práticas que circularam e viajaram entre a Itália e a Espanha, por meio dos contadores de radioatividade, construíram e influenciaram tanto a energia nuclear e o poder político durante o regime de Franco. O trabalho revela pessoas, materiais, instrumentos e conhecimentos itinerantes que nos permite pensar nos cientistas espanhóis e no seu papel na circulação de material e conhecimento científicos, ao mesmo tempo que atuaram como vetores das relações diplomáticas e políticas da época.
Subject(s)
Humans , History, 20th Century , Science , Spain , Knowledge , ItalyABSTRACT
Objective: To identify and isolate phenolic compounds from Cuspidaria convoluta, and to evaluate their antibacterial activity and synergistic effect with antibiotics. Methods: The crude extract was prepared by maceration with methanol (5%). The dry extract was suspended in water and fractionated successively. The most active extract was selected by its antibacterial activity and its total phenol content was determined by spectrophotometry and by HPLC-MS/MS. Bioactive fractions of the most active extract were separated by column chromatography and evaluated by bioautography. Isolated compounds were identified. Minimum inhibitory concentration (MIC) of these compounds was determined by microdilution broth method, and synergism with antibiotics (ampicillin, gentamicin and oxacillin) was tested by checkerboard and time-kill assays. Results: Coumaric acid, catechin/epicatechin, and luteolin were purified and identified from the extract. There was an increase in the antibacterial activity of antibiotics when they were combined with these compounds. The combination of luteolin and ampicillin had the most potent antibacterial activities. The MICs of oxacillin for each of methicillin-resistant Staphylococcus aureus strains were reduced between 4 and 8-fold when these strains were coincubated with sub-MIC (≤ ½ MIC) levels of these compounds, demonstrating that the combination had synergistic effect for all cases. Conclusions: Cuspidaria convoluta contains important pharmacologically active substances that can be used to improve antibiotic efficacy.
ABSTRACT
El objetivo del presente trabajo fue examinar la violencia relacional entre iguales desde una perspectiva psicosocial, analizando variables familiares (funcionamiento y comunicación familiar), sociales (reputación social - percibida e ideal - y actitud hacia la autoridad institucional) e individuales (malestar psicológico e ideación suicida) en adolescentes escolarizados. La muestra fue de 8115 adolescentes, con edades comprendidas entre los 11 y los 16 años, del estado de Nuevo León, México. Se realizó un análisis de regresión lineal múltiple, paso a paso, cuyos resultados mostraron que la dimensión más importante en la predicción de la conducta violenta relacional es la autopercepción no conformista, seguido del malestar psicológico. Finalmente, se discuten estos resultados y sus implicaciones.
The aim of this research was to study relational violence between peers from a psychosocial perspective, by analyzing family variables (family functioning and communication), social variables (social reputation both perceived and ideal and attitude towards institutional authority), and individual variables (psychological distress and suicide ideation) in adolescent students. The sample consisted of 8,115 adolescents aged 11 to 16 years from the State of Nuevo León, Mexico. We performed a forward stepwise multiple regression analysis, the results of which showed that the most important factor in the prediction of violent relational behavior at school is the nonconformist self-perception, followed by psychological distress. Finally, these results and their implications are discussed.